Ontology highlight
ABSTRACT:
SUBMITTER: Chuanyin L
PROVIDER: S-EPMC5675682 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Chuanyin Li L Xiaona Wang W Zhiling Yan Y Yu Zhang Z Shuyuan Liu L Jie Yang Y Chao Hong H Li Shi S Hongying Yang Y Yufeng Yao Y
Oncotarget 20170923 50
Several studies have confirmed the crucial roles of microRNAs (miRNAs) in cancer occurrence. In addition, single nucleotide polymorphisms (SNPs) in miRNA genes have been associated with various cancers. The aim of the present study was to investigate the association of SNPs in miRNA genes with cervical intraepithelial neoplasia (CIN) and cervical cancer in a Chinese Han population. We searched SNPs in nineteen miRNAs by sequencing healthy individuals (n=50). Then, a total of 400 patients with CI ...[more]