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ERCP in infants, children and adolescents is feasible and safe: results from a tertiary care center.


ABSTRACT: Indications for endoscopic retrograde cholangiopancreatography (ERCP) in children differ from adults. Paucity of data and concerns about potential lower effectiveness and more side effects limit its use even in high volume centers. We retrospectively analyzed indications, success rates, limitations, and side effects of ERCPs in children <18 years.From January 2012 to March 2015, 54 ERCPs were performed in 31 children (median age 11 (0-17) years; median weight 22 (3.3-142.7) kg) with suspected choledocholithiasis (n?=?13 interventions in 9 patients), post-transplantation anastomotic stenosis (10/4), malignancy (10/5), chronic pancreatitis (7/1), biliary atresia (6/6), anomaly (2/2), leak (4/3), or primary sclerosing cholangitis (PSC) (2/1). All patients were followed up as inpatients.Thirty-six therapeutic and 18 diagnostic procedures were performed by adult ERCP expert endoscopists. Successful intervention was achieved in 90.7% of cases. Failed cannulation (n?=?4) was associated with lower body weight (p?=?0.023). In children younger than 1 year, ERCP was significantly more often diagnostic than in patients >1 year (p?

SUBMITTER: Felux J 

PROVIDER: S-EPMC5676540 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature

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ERCP in infants, children and adolescents is feasible and safe: results from a tertiary care center.

Felux Jasmin J   Sturm Ekkehard E   Busch Andreas A   Zerabruck Emanuel E   Graepler Florian F   Stüker Dietmar D   Manger Andreas A   Kirschner Hans-Joachim HJ   Blumenstock Gunnar G   Malek Nisar P NP   Goetz Martin M  

United European gastroenterology journal 20170111 7


<h4>Background</h4>Indications for endoscopic retrograde cholangiopancreatography (ERCP) in children differ from adults. Paucity of data and concerns about potential lower effectiveness and more side effects limit its use even in high volume centers. We retrospectively analyzed indications, success rates, limitations, and side effects of ERCPs in children <18 years.<h4>Methods</h4>From January 2012 to March 2015, 54 ERCPs were performed in 31 children (median age 11 (0-17) years; median weight 2  ...[more]

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