An Alternative Method to Characterize the Quasi-Static, Nonlinear Material Properties of Murine Articular Cartilage.
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ABSTRACT:
SUBMITTER: Kotelsky A
PROVIDER: S-EPMC5676653 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Publications
An Alternative Method to Characterize the Quasi-Static, Nonlinear Material Properties of Murine Articular Cartilage.
Kotelsky Alexander A Woo Chandler W CW Delgadillo Luis F LF Richards Michael S MS Buckley Mark R MR
Journal of biomechanical engineering 20180101 1
With the onset and progression of osteoarthritis (OA), articular cartilage (AC) mechanical properties are altered. These alterations can serve as an objective measure of tissue degradation. Although the mouse is a common and useful animal model for studying OA, it is extremely challenging to measure the mechanical properties of murine AC due to its small size (thickness < 50 μm). In this study, we developed novel and direct approach to independently quantify two quasi-static mechanical propertie ...[more]
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