CXCL10/CXCR3 axis is associated with disease activity and the development of mucocutaneous lesions in patients with Behcet's disease.
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ABSTRACT:
SUBMITTER: Lee SJ
PROVIDER: S-EPMC5677118 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
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CXCL10/CXCR3 axis is associated with disease activity and the development of mucocutaneous lesions in patients with Behçet's disease.
Lee Sang Jin SJ Kang Shin Eui SE Kang Eun Ha EH Choi Byoong Yong BY Masek-Hammerman Katherine K Syed Jameel J Zhan Yutian Y Neff-Phillips Kathleen K Park Jin Kyun JK Lee Eun Young EY Lee Eun Bong EB Song Yeong Wook YW
Scientific reports 20171107 1
The objective of this study was to investigate CXC chemokines and its receptor in patients with Behcet's disease (BD) and their associations with disease activity. Blood samples were collected from 109 BD patients and 36 age- and sex-matched healthy controls (HCs). Twenty-two follow-up blood samples were collected in BD patients. Serum CXC chemokines (CXCL1, CXCL8, CXCL9, CXCL10, CXCL12, CXCL13 and CXCL16) and cell surface marker expression (CD3, CD4 and CXCR3) in peripheral blood mononuclear ce ...[more]
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