Ontology highlight
ABSTRACT:
SUBMITTER: Cengiz FB
PROVIDER: S-EPMC5679420 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Cengiz Filiz Basak FB Yilmazer Rasim R Olgun Levent L Sennaroglu Levent L Kirazli Tayfun T Alper Hudaver H Olgun Yuksel Y Incesulu Armagan A Atik Tahir T Huesca-Hernandez Fabiola F Domínguez-Aburto Juan J González-Rosado Garly G Hernandez-Zamora Edgar E Arenas-Sordo Maria de la Luz ML Menendez Ibis I Orhan Kadir Serkan KS Avci Hakan H Mahdieh Nejat N Bonyadi Mortaza M Foster Joseph J Duman Duygu D Ozkinay Ferda F Blanton Susan H SH Bademci Guney G Tekin Mustafa M
International journal of pediatric otorhinolaryngology 20170808
<h4>Objectives</h4>The genetics of sensorineural hearing loss is characterized by a high degree of heterogeneity. Despite this heterogeneity, DNA variants found within SLC26A4 have been reported to be the second most common contributor after those of GJB2 in many populations.<h4>Methods</h4>Whole exome sequencing and/or Sanger sequencing of SLC26A4 in 117 individuals with sensorineural hearing loss with or without inner ear anomalies but not with goiter from Turkey, Iran, and Mexico were perform ...[more]