Ontology highlight
ABSTRACT:
SUBMITTER: Xu X
PROVIDER: S-EPMC5681219 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Xu Xiaoding X Saw Phei Er PE Tao Wei W Li Yujing Y Ji Xiaoyuan X Bhasin Sushant S Liu Yanlan Y Ayyash Dana D Rasmussen Jonathan J Huo Marc M Shi Jinjun J Shi Jinjun J Farokhzad Omid C OC Farokhzad Omid C OC
Advanced materials (Deerfield Beach, Fla.) 20170706 33
The application of nanoparticles (NPs) to drug delivery has led to the development of novel nanotherapeutics for the treatment of various diseases including cancer. However, clinical use of NP-mediated drug delivery has not always translated into improved survival of cancer patients, in part due to the suboptimal properties of NP platforms, such as premature drug leakage during preparation, storage, or blood circulation, lack of active targeting to tumor tissue and cells, and poor tissue penetra ...[more]