Effect of New Oral Anticoagulants on Prescribing Practices for Atrial Fibrillation in Older Adults.

ABSTRACT:

Objectives

To determine the effect of new oral anticoagulants (NOACs) on prescribing practices in older adults with atrial fibrillation (AF).

Design

Retrospective observational cohort study.

Setting

Academic medical center in St. Louis, Missouri.

Participants

Individuals aged 75 and older with AF admitted to the hospital from October 2010 through September 2015 (N = 6,568, 50% female, 15% non-white).

Measurements

Information on NOACs and warfarin prescribed at discharge was obtained from hospital discharge summaries, and linear regression was used to examine quarterly trends in their use. Multivariable logistic regression was used to assess independent predictors of anticoagulant use.

Results

NOAC use increased over time (correlation coefficient (

SUBMITTER: Fohtung RB 

PROVIDER: S-EPMC5681366 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature