Ontology highlight
ABSTRACT:
SUBMITTER: Box JM
PROVIDER: S-EPMC5683760 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Box Jodie M JM Kaur Jasvinder J Stuart Rosemary A RA
Molecular biology of the cell 20170920 24
Mitoribosomes perform the synthesis of the core components of the oxidative phosphorylation (OXPHOS) system encoded by the mitochondrial genome. We provide evidence that MrpL35 (mL38), a mitospecific component of the yeast mitoribosomal central protuberance, assembles into a subcomplex with MrpL7 (uL5), Mrp7 (bL27), and MrpL36 (bL31) and mitospecific proteins MrpL17 (mL46) and MrpL28 (mL40). We isolated respiratory defective <i>mrpL35</i> mutant yeast strains, which do not display an overall inh ...[more]