Ontology highlight
ABSTRACT:
SUBMITTER: Laband K
PROVIDER: S-EPMC5684144 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Laband Kimberley K Le Borgne Rémi R Edwards Frances F Stefanutti Marine M Canman Julie C JC Verbavatz Jean-Marc JM Dumont Julien J
Nature communications 20171114 1
During cell division, spindle microtubules ensure an equal repartition of chromosomes between the two daughter cells. While the kinetochore-dependent mechanisms that drive mitotic chromosome segregation are well understood, in oocytes of most species atypical spindles assembled in absence of centrosomes entail poorly understood mechanisms of chromosome segregation. In particular, the structure(s) responsible for force generation during meiotic chromosome separation in oocytes is unclear. Using q ...[more]