Ontology highlight
ABSTRACT:
SUBMITTER: Johnson KC
PROVIDER: S-EPMC5685890 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Johnson Karen C KC Bray George A GA Cheskin Lawrence J LJ Clark Jeanne M JM Egan Caitlin M CM Foreyt John P JP Garcia Katelyn R KR Glasser Stephen S Greenway Frank L FL Gregg Edward W EW Hazuda Helen P HP Hergenroeder Andrea A Hill James O JO Horton Edward S ES Jakicic John M JM Jeffery Robert W RW Kahn Steven E SE Knowler William C WC Lewis Cora E CE Miller Marsha M Montez Maria G MG Nathan David M DM Patricio Jennifer L JL Peters Anne L AL Pi-Sunyer Xavier X Pownall Henry J HJ Reboussin David D Redmon J Bruce JB Steinberg Helmut H Wadden Thomas A TA Wagenknecht Lynne E LE Wing Rena R RR Womack Catherine R CR Yanovski Susan Z SZ Zhang Ping P Schwartz Ann V AV
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20170728 11
Intentional weight loss is an important treatment option for overweight persons with type 2 diabetes mellitus (DM), but the effects on long-term fracture risk are not known. The purpose of this Look AHEAD analysis was to evaluate whether long-term intentional weight loss would increase fracture risk in overweight or obese persons with DM. Look AHEAD is a multicenter, randomized clinical trial. Recruitment began in August 2001 and follow-up continued for a median of 11.3 years at 16 academic cent ...[more]