Ontology highlight
ABSTRACT:
SUBMITTER: Su MY
PROVIDER: S-EPMC5686067 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Su Ming-Yuan MY Som Nilanjan N Wu Chia-Yun CY Su Shih-Chieh SC Kuo Yi-Ting YT Ke Lu-Chu LC Ho Meng-Ru MR Tzeng Shiou-Ru SR Teng Ching-Hao CH Mengin-Lecreulx Dominique D Reddy Manjula M Chang Chung-I CI
Nature communications 20171115 1
Peptidoglycan (PG) is a highly cross-linked, protective mesh-like sacculus that surrounds the bacterial cytoplasmic membrane. Expansion of PG is tightly coupled to growth of a bacterial cell and requires hydrolases to cleave the cross-links for insertion of nascent PG material. In Escherichia coli, a proteolytic system comprising the periplasmic PDZ-protease Prc and the lipoprotein adaptor NlpI contributes to PG enlargement by regulating cellular levels of MepS, a cross-link-specific hydrolase. ...[more]