Ontology highlight
ABSTRACT:
SUBMITTER: Wagner R
PROVIDER: S-EPMC5686126 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Wagner Róbert R Tabák Ádám G ÁG Fehlert Ellen E Fritsche Louise L Jaghutriz Benjamin A BA Bánhegyi Róbert J RJ Schmid Sebastian M SM Staiger Harald H Machicao Fausto F Peter Andreas A Häring Hans-Ulrich HU Fritsche Andreas A Heni Martin M
Scientific reports 20171114 1
Variation in FTO is the most important common genetic determinant of body weight. Altered energy metabolism could underlie this association. We hypothesized that higher circulating glucose or triglycerides can amplify the FTO impact on BMI. In 2671 subjects of the TUEF study, we investigated the interaction effect of fasting glucose and triglyceride levels with rs9939609 in FTO on BMI. We analysed the same interaction effect by longitudinally utilizing mixed effect models in the prospective Whit ...[more]