Ontology highlight
ABSTRACT:
SUBMITTER: Lundell AC
PROVIDER: S-EPMC5686210 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Lundell Anna-Carin AC Nordström Inger I Andersson Kerstin K Strömbeck Anna A Ohlsson Claes C Tivesten Åsa Å Rudin Anna A
Scientific reports 20171114 1
Boys present with higher proportions of immature/naïve CD5<sup>+</sup> B cells than girls up to 3 years of age. Boys also have higher fractions of regulatory T cells (Tregs) in early infancy, but the mechanisms for these sex-related differences are unknown. In the prospective FARMFLORA follow-up study of 23 boys and 25 girls, we investigated if these immunological differences remained at 8 years of age. We also examined if testosterone or dihydrotestosterone (DHT) levels at birth and at 8 years ...[more]