Methodology for Computational Fluid Dynamic Validation for Medical Use: Application to Intracranial Aneurysm.

ABSTRACT: Computational fluid dynamics (CFD) is a promising tool to aid in clinical diagnoses of cardiovascular diseases. However, it uses assumptions that simplify the complexities of the real cardiovascular flow. Due to high-stakes in the clinical setting, it is critical to calculate the effect of these assumptions in the CFD simulation results. However, existing CFD validation approaches do not quantify error in the simulation results due to the CFD solver's modeling assumptions. Instead, they directly compare CFD simulation results against validation data. Thus, to quantify the accuracy of a CFD solver, we developed a validation methodology that calculates the CFD model error (arising from modeling assumptions). Our methodology identifies independent error sources in CFD and validation experimen

SUBMITTER: Paliwal N 

PROVIDER: S-EPMC5686786 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature