Renal-Clearable PEGylated Porphyrin Nanoparticles for Image-guided Photodynamic Cancer Therapy.
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ABSTRACT:
SUBMITTER: Cheng L
PROVIDER: S-EPMC5687274 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Publications
Renal-Clearable PEGylated Porphyrin Nanoparticles for Image-guided Photodynamic Cancer Therapy.
Cheng Liang L Jiang Dawei D Kamkaew Anyanee A Valdovinos Hector F HF Im Hyung-Jun HJ Feng Liangzhu L England Christopher G CG Goel Shreya S Barnhart Todd E TE Liu Zhuang Z Cai Weibo W
Advanced functional materials 20170726 34
Noninvasive dynamic positron emission tomography (PET) imaging was used to investigate the balance between renal clearance and tumor uptake behaviors of polyethylene glycol (PEG)-modified porphyrin nanoparticles (TCPP-PEG) with various molecular weights. TCPP-PEG<sub>10K</sub> nanoparticles with clearance behavior would be a good candidate for PET image-guided photodynamic therapy. ...[more]
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