Ontology highlight
ABSTRACT:
SUBMITTER: Langenstroth-Rower D
PROVIDER: S-EPMC5687340 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Langenstroth-Röwer Daniel D Gromoll Jörg J Wistuba Joachim J Tröndle Ina I Laurentino Sandra S Schlatt Stefan S Neuhaus Nina N
Epigenetics 20161027 7
The timing of de novo DNA methylation in male germ cells during human testicular development is yet unsolved. Apart from that, the stability of established imprinting patterns in vitro is controversially discussed. This study aimed at determining the timing of DNA de novo methylation and at assessing the stability of the methylation status in vitro. We employed the marmoset monkey (Callithrix jacchus) as it is considered the best non-human primate model for human testicular development. We selec ...[more]