Ontology highlight
ABSTRACT:
SUBMITTER: Balikov DA
PROVIDER: S-EPMC5687519 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Balikov Daniel A DA Crowder Spencer W SW Boire Timothy C TC Lee Jung Bok JB Gupta Mukesh K MK Fenix Aidan M AM Lewis Holley N HN Ambrose Caitlyn M CM Short Philip A PA Kim Chang Soo CS Burnette Dylan T DT Reilly Matthew A MA Murthy N Sanjeeva NS Kang Mi-Lan ML Kim Won Shik WS Sung Hak-Joon HJ
ACS applied materials & interfaces 20170629 27
Human bone marrow derived mesenchymal stem cells (hMSCs) hold great promise for regenerative medicine due to their multipotent differentiation capacity and immunomodulatory capabilities. Substantial research has elucidated mechanisms by which extracellular cues regulate hMSC fate decisions, but considerably less work has addressed how material properties can be leveraged to maintain undifferentiated stem cells. Here, we show that synthetic culture substrates designed to exhibit moderate cell-rep ...[more]