Ontology highlight
ABSTRACT:
SUBMITTER: Xu G
PROVIDER: S-EPMC5687757 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Xu Guang G Walker David H DH Jupiter Daniel D Melby Peter C PC Arcari Christine M CM
PLoS neglected tropical diseases 20171103 11
Scrub typhus is a serious public health problem in the Asia-Pacific area. It threatens one billion people globally, and causes illness in one million people each year. Caused by Orientia tsutsugamushi, scrub typhus can result in severe multiorgan failure with a case fatality rate up to 70% without appropriate treatment. The antigenic heterogeneity of O. tsutsugamushi precludes generic immunity and allows reinfection. As a neglected disease, there is still a large gap in our knowledge of the dise ...[more]