Ontology highlight
ABSTRACT:
SUBMITTER: Ferretti E
PROVIDER: S-EPMC5689608 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Ferretti Elisa E Hohaus Stefan S Di Napoli Arianna A Belmonte Beatrice B Cuccaro Annarosa A Cupelli Elisa E Galli Eugenio E Rufini Vittoria V Tripodi Gino G Fraternali-Orcioni Giulio G Pistoia Vito V Corcione Anna A
Oncotarget 20170728 49
Hodgkin Lymphoma (HL) is a tumor of B-cell origin characterized by Hodgkin and Reed-Stenberg (H/RS) cells embedded in an inflammatory tissue where numerous cytokines/chemokines contribute to shape the microenvironment, leading to the typical clinical symptoms. We investigated: i) the expression of Interleukin-IL-31 (IL-31) and Thymic Stromal Lymphopoietin (TSLP), two Th2-related cytokines with tumor-promoting and pruritogenic functions, and of the respective receptors in HL invaded lymph nodes b ...[more]