Ontology highlight
ABSTRACT:
SUBMITTER: Katsanos D
PROVIDER: S-EPMC5690688 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Katsanos Dimitris D Koneru Sneha L SL Mestek Boukhibar Lamia L Gritti Nicola N Ghose Ritobrata R Appleford Peter J PJ Doitsidou Maria M Woollard Alison A van Zon Jeroen S JS Poole Richard J RJ Barkoulas Michalis M
PLoS biology 20171106 11
Biological systems are subject to inherent stochasticity. Nevertheless, development is remarkably robust, ensuring the consistency of key phenotypic traits such as correct cell numbers in a certain tissue. It is currently unclear which genes modulate phenotypic variability, what their relationship is to core components of developmental gene networks, and what is the developmental basis of variable phenotypes. Here, we start addressing these questions using the robust number of Caenorhabditis ele ...[more]