Ontology highlight
ABSTRACT:
SUBMITTER: Gurruchaga H
PROVIDER: S-EPMC5691190 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Gurruchaga Haritz H Saenz Del Burgo Laura L Garate Ane A Delgado Diego D Sanchez Pello P Orive Gorka G Ciriza Jesús J Sanchez Mikel M Pedraz Jose Luis JL
Scientific reports 20171116 1
Transplantation of mesenchymal stem cells (MSCs) has emerged as an alternative strategy to treat knee osteoarthritis. In this context, MSCs derived from synovial fluid could provide higher chondrogenic and cartilage regeneration, presenting synovial fluid as an appropriate MSCs source. An allogeneic and biomimetic bioscaffold composed of Platelet Rich Plasma and synovial fluid that preserve and mimics the natural environment of MSCs isolated from knee has also been developed. We have optimized t ...[more]