Ontology highlight
ABSTRACT:
SUBMITTER: Snyder CM
PROVIDER: S-EPMC5691604 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Snyder Christa M CM Zhou Xiaomei X Karty Jonathan A JA Fonslow Bryan R BR Novotny Milos V MV Jacobson Stephen C SC
Journal of chromatography. A 20170909
Through direct coupling of capillary electrophoresis (CE) to mass spectrometry (MS) with a sheathless interface, we have identified 77 potential N-glycan structures derived from human serum. We confirmed the presence of N-glycans previously identified by indirect methods, e.g., electrophoretic mobility standards, obtained 31 new N-glycan structures not identified in our prior work, differentiated co-migrating structures, and determined specific linkages on isomers featuring sialic acids. Serum N ...[more]