Ontology highlight
ABSTRACT:
SUBMITTER: Espinosa-Medina I
PROVIDER: S-EPMC5692562 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Espinosa-Medina Isabel I Jevans Ben B Boismoreau Franck F Chettouh Zoubida Z Enomoto Hideki H Müller Thomas T Birchmeier Carmen C Burns Alan J AJ Brunet Jean-François JF
Proceedings of the National Academy of Sciences of the United States of America 20171024 45
Most of the enteric nervous system derives from the "vagal" neural crest, lying at the level of somites 1-7, which invades the digestive tract rostro-caudally from the foregut to the hindgut. Little is known about the initial phase of this colonization, which brings enteric precursors into the foregut. Here we show that the "vagal crest" subsumes two populations of enteric precursors with contrasted origins, initial modes of migration, and destinations. Crest cells adjacent to somites 1 and 2 pr ...[more]