Ontology highlight
ABSTRACT:
SUBMITTER: Nolan SJ
PROVIDER: S-EPMC5695111 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Nolan Sabrina J SJ Fu Man Shun MS Coppens Isabelle I Casadevall Arturo A
Infection and immunity 20171117 12
Many microbes exploit host cellular lipid droplets during the host-microbe interaction, but this phenomenon has not been extensively studied for fungal pathogens. In this study, we analyzed the role of lipid droplets during the interaction of <i>Cryptococcus neoformans</i> with macrophages in the presence and the absence of exogenous lipids, in particular, oleate. The addition of oleic acid increased the frequency of lipid droplets in both <i>C. neoformans</i> and macrophages<i>. C. neoformans</ ...[more]