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Lipid profiles and determinants of total cholesterol and hypercholesterolaemia among 25-74 year-old urban and rural citizens of the Yangon Region, Myanmar: a cross-sectional study.


ABSTRACT: OBJECTIVE:The first is to estimate the prevalence of dyslipidaemia (hypercholesterolaemia, hypertriglyceridaemia, high low-density lipoprotein (LDL) level and low high-density lipoprotein (HDL) level), as well as the mean levels of total cholesterol, triglyceride, LDL and HDL, in the urban and rural Yangon Region, Myanmar. The second is to investigate the association between urban-rural location and total cholesterol. DESIGN:Two cross-sectional studies using the WHO STEPS methodology. SETTING:Both the urban and rural areas of the Yangon Region, Myanmar. PARTICIPANTS:A total of 1370 men and women aged 25-74 years participated based on a multistage cluster sampling. Physically and mentally ill people, monks, nuns, soldiers and institutionalised people were excluded. RESULTS:Compared with rural counterparts, urban dwellers had a significantly higher age-standardised prevalence of hypercholesterolaemia (50.7% vs 41.6%; p=0.042) and a low HDL level (60.6% vs 44.4%; p=0.001). No urban-rural differences were found in the prevalence of hypertriglyceridaemia and high LDL. Men had a higher age-standardised prevalence of hypertriglyceridaemia than women (25.1% vs 14.8%; p<0.001), while the opposite pattern was found in the prevalence of a high LDL (11.3% vs 16.3%; p=0.018) and low HDL level (35.3% vs 70.1%; p<0.001).Compared with rural inhabitants, urban dwellers had higher age-standardised mean levels of total cholesterol (5.31?mmol/L, SE: 0.044 vs 5.05?mmol/L, 0.068; p=0.009), triglyceride (1.65?mmol/L, 0.049 vs 1.38?mmol/L, 0.078; p=0.017), LDL (3.44?mmol/L, 0.019 vs 3.16?mmol/L, 0.058; p=0.001) and lower age-standardised mean levels of HDL (1.11?mmol/L, 0.010 vs 1.25?mmol/L, 0.012; p<0.001). In linear regression, the total cholesterol was significantly associated with an urban location among men, but not among women. CONCLUSION:The mean level of total cholesterol and the prevalence of hypercholesterolaemia were alarmingly high in men and women in both the urban and rural areas of Yangon Region, Myanmar. Preventive measures to reduce cholesterol levels in the population are therefore needed.

SUBMITTER: Htet AS 

PROVIDER: S-EPMC5695408 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature

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Lipid profiles and determinants of total cholesterol and hypercholesterolaemia among 25-74 year-old urban and rural citizens of the Yangon Region, Myanmar: a cross-sectional study.

Htet Aung Soe AS   Kjøllesdal Marte Karoline MK   Aung Wai Phyo WP   Moe Myint Aye Nyein AN   Aye Win Thuzar WT   Wai Myint Myint MM   Nu Than Than TT   Hla Ei Mon EM   Soe Pyone Pyone PP   Tun Nan Wut Yi NWY   Angela Naw N   Khaing Mya Mya MM   Htoo Aung Kyaw AK   Tun Soe S   Thitsar Pai P   Lwin Theeoo T   Wai San San SS   Aung Thi Thi TT   Thant Khin Aye KA   Aung Po Wai Wai WW   Gauzam Seng Taung ST   Naing Tun Tun TT   Tun Thet Min TM   Myint Khin San KS   Oo Kyi Kyi KK   Mang Nang Kee Myu NKM   Naing Soe Moe SM   Zaw Ko Ko KK   Bjertness Marius Bergsmark MB   Sherpa Lhamo Yangchen LY   Oo Win Myint WM   Stigum Hein H   Bjertness Espen E  

BMJ open 20171115 11


<h4>Objective</h4>The first is to estimate the prevalence of dyslipidaemia (hypercholesterolaemia, hypertriglyceridaemia, high low-density lipoprotein (LDL) level and low high-density lipoprotein (HDL) level), as well as the mean levels of total cholesterol, triglyceride, LDL and HDL, in the urban and rural Yangon Region, Myanmar. The second is to investigate the association between urban-rural location and total cholesterol.<h4>Design</h4>Two cross-sectional studies using the WHO STEPS methodol  ...[more]

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