Ontology highlight
ABSTRACT:
SUBMITTER: Williams A
PROVIDER: S-EPMC5695571 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Williams Asher A He Wenqin W Cress Brady F BF Liu Xinyue X Alexandria Jordanne J Yoshizawa Hiroki H Nishimura Kazuhiro K Toida Toshihiko T Koffas Mattheos M Linhardt Robert J RJ
Biotechnology journal 20170904 10
Chondroitin sulfates are the glycosaminoglycan chains of proteoglycans critical in the normal development and pathophysiology of all animals. Chondroitinase ACII, a polysaccharide lyase originally isolated from Arthrobacter aurescens IAM 110 65, which is widely used in the analysis and study of chondroitin structure, is no longer commercially available. The aim of the current study is to prepare recombinant versions of this critical enzyme for the glycobiology research community. Two versions of ...[more]