Ontology highlight
ABSTRACT:
SUBMITTER: Wang F
PROVIDER: S-EPMC5696162 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Wang Fei F Wu Dinglan D Fu Housheng H He Fengrong F Xu Congjie C Zhou Jiaquan J Li Daoyuan D Li Guoping G Xu Jianbing J Wu Qinghui Q Chen Jianxiang J Su Liangju L Wang Weifu W Zhang Shufang S
Oncotarget 20170906 54
Earlier reports demonstrated that Cofilin expression is increased in bladder cancer samples, though its function remains unknown. Here, we found that Cofilin 1 expression was higher in bladder cancer tissues than in paracancerous tissues. Overexpression of Cofilin 1 promoted, while Cofilin 1 knockdown inhibited, proliferation, migration, and invasion in the T24 and RT4 bladder cancer cell lines. In addition, Cofilin 1 overexpression increased, while Cofilin 1 knockdown decreased, bladder tumor v ...[more]