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Gibbs free energy as a measure of complexity correlates with time within C. elegans embryonic development.

ABSTRACT: We investigate free energy behavior in the nematode Caenorhabditis elegans during embryonic development. Our approach utilizes publicly available gene expression data, which gives us a picture of developmental changes in protein concentration and, resultantly, chemical potential and free energy. Our results indicate a clear global relationship between Gibbs free energy and time spent in development and provide thermodynamic indicators of the large-scale biological events of cell division and differentiation.

SUBMITTER: McGuire SH

PROVIDER: S-EPMC5696307 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature

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Gibbs free energy as a measure of complexity correlates with time within C. elegans embryonic development.

McGuire Samuel H SH Rietman Edward A EA Siegelmann Hava H Tuszynski Jack A JA

Journal of biological physics 20170919 4

We investigate free energy behavior in the nematode Caenorhabditis elegans during embryonic development. Our approach utilizes publicly available gene expression data, which gives us a picture of developmental changes in protein concentration and, resultantly, chemical potential and free energy. Our results indicate a clear global relationship between Gibbs free energy and time spent in development and provide thermodynamic indicators of the large-scale biological events of cell division and dif ...[more]

PMID: 28929407

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PCR cycles affect gibbs free energy bias

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PCR cycles affect gibbs free energy bias

Project description:PCR cycles affect gibbs free energy bias

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