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Application of the qSOFA score to predict mortality in patients with suspected infection in a resource-limited setting in Malawi.


ABSTRACT:

Purpose

To determine the predictive value of qSOFA (quick Sequential Organ Failure Assessment) in Malawian patients with suspected infection.

Methods

Prospective observational study in a tertiary referral hospital in Malawi.

Results

Predictive ability of qSOFA was reasonable [AUROC 0.73 (95% CI 0.68-0.78)], increasing to 0.77 (95% CI 0.72-0.82) when classifying all patients with altered mental status as high risk. Adding HIV status as a variable to the qSOFA score did not improve predictive value.

Conclusion

qSOFA is a simple tool that can aid risk stratification in resource-limited settings.

SUBMITTER: Huson MAM 

PROVIDER: S-EPMC5696439 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature

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Publications

Application of the qSOFA score to predict mortality in patients with suspected infection in a resource-limited setting in Malawi.

Huson Michaëla A M MAM   Katete Chawezi C   Chunda Lilian L   Ngoma Jonathan J   Wallrauch Claudia C   Heller Tom T   van der Poll Tom T   Grobusch Martin P MP  

Infection 20170807 6


<h4>Purpose</h4>To determine the predictive value of qSOFA (quick Sequential Organ Failure Assessment) in Malawian patients with suspected infection.<h4>Methods</h4>Prospective observational study in a tertiary referral hospital in Malawi.<h4>Results</h4>Predictive ability of qSOFA was reasonable [AUROC 0.73 (95% CI 0.68-0.78)], increasing to 0.77 (95% CI 0.72-0.82) when classifying all patients with altered mental status as high risk. Adding HIV status as a variable to the qSOFA score did not i  ...[more]

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