Ontology highlight
ABSTRACT:
SUBMITTER: Huang L
PROVIDER: S-EPMC5696562 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Cell chemical biology 20171005 11
Riboswitches are structural elements found in mRNA molecules that couple small-molecule binding to regulation of gene expression, usually by controlling transcription or translation. We have determined high-resolution crystal structures of the ykkC guanidine III riboswitch from Thermobifida fusca. The riboswitch forms a classic H-type pseudoknot that includes a triple helix that is continuous with a central core of conserved nucleotides. These form a left-handed helical ramp of inter-nucleotide ...[more]