Cortical mapping of painful electrical stimulation by quantitative electroencephalography: unraveling the time-frequency-channel domain.

ABSTRACT: The goal of this study was to capture the electroencephalographic signature of experimentally induced pain and pain-modulating mechanisms after painful peripheral electrical stimulation to determine one or a selected group of electrodes at a specific time point with a specific frequency range. In the first experiment, ten healthy participants were exposed to stimulation of the right median nerve while registering brain activity using 32-channel electroencephalography. Electrical stimulations were organized in four blocks of 20 stimuli with four intensities - 100%, 120%, 140%, and 160% - of the electrical pain threshold. In the second experiment, 15 healthy participants received electrical stimulation on the dominant median nerve before and during the application of a second painful stimulu

SUBMITTER: Goudman L 

PROVIDER: S-EPMC5697445 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature