Ontology highlight
ABSTRACT:
SUBMITTER: Parikh CR
PROVIDER: S-EPMC5698070 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Parikh Chirag R CR Puthumana Jeremy J Shlipak Michael G MG Koyner Jay L JL Thiessen-Philbrook Heather H McArthur Eric E Kerr Kathleen K Kavsak Peter P Whitlock Richard P RP Garg Amit X AX Coca Steven G SG
Journal of the American Society of Nephrology : JASN 20170814 12
Clinical AKI, measured by serum creatinine elevation, is associated with long-term risks of adverse cardiovascular (CV) events and mortality in patients after cardiac surgery. To evaluate the relative contributions of urine kidney injury biomarkers and plasma cardiac injury biomarkers in adverse events, we conducted a multicenter prospective cohort study of 968 adults undergoing cardiac surgery. On postoperative days 1-3, we measured five urine biomarkers of kidney injury (IL-18, NGAL, KIM-1, L- ...[more]