Ontology highlight
ABSTRACT:
SUBMITTER: Deng YQ
PROVIDER: S-EPMC5698318 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Deng Yong-Qiang YQ Zhang Na-Na NN Li Xiao-Feng XF Wang Ya-Qing YQ Tian Min M Qiu Ye-Feng YF Fan Jun-Wan JW Hao Jia-Nan JN Huang Xing-Yao XY Dong Hao-Long HL Fan Hang H Wang Yu-Guang YG Zhang Fu-Chun FC Tong Yi-Gang YG Xu Zhiheng Z Qin Cheng-Feng CF
Nature communications 20171121 1
Zika virus (ZIKV) is primarily transmitted to humans through mosquito bites or sexual contact. The excretion and persistence of contagious ZIKV in various body fluids have been well documented in ZIKV patients; however, the risk of direct contact exposure remains unclear. Here, we show that guinea pigs are susceptible to ZIKV infection via subcutaneous inoculation route; infected guinea pigs exhibit seroconversion and significant viral secretion in sera, saliva, and tears. Notably, ZIKV is effic ...[more]