Dataset Information

Serum Total Testosterone Concentrations in the US Household Population from the NHANES 2011-2012 Study Population.

ABSTRACT: BACKGROUND:Limited information is available about testosterone concentrations representative of the general US population, especially children, women, and non-Hispanic Asians. METHODS:We obtained nationally representative data for total testosterone (totalT), measured with standardized LC-MS/MS, for the US population age 6 years and older from the 2011-2012 National Health and Nutrition Examination Survey (NHANES). We analyzed 6746 serum samples and calculated the geometric means, distribution percentiles, and covariate-adjusted geometric means by age, sex, and race/ethnicity. RESULTS:The 10th-90th percentiles of totalT values in adults (?20 years) was 150-698 ng/dL (5.20-24.2 nmol/L) in men, 7.1-49.8 ng/dL (0.25-1.73 nmol/L) in women, and 1.0-9.5 ng/dL (0.04-0.33 nmol/L) in children (6-10 years old). Differences among race/ethnic groups existed in children and men: covariate-adjusted totalT values in non-Hispanic Asians were highest among children (58% compared to non-Hispanic black children) and lowest among men (12% compared to Mexican-American men). Covariate-adjusted totalT values in men were higher at age 55-60 years compared to ages 35 and 80 years, a pattern different from that observed in previous NHANES cycles. CONCLUSIONS:TotalT patterns were different among age groups in men compared with previous NHANES cycles. Covariate-adjusted totalT values peaked at age 55-60 years in men, which appeared to be consistent with the increased use of exogenous testosterone. Differences among race/ethnic groups existed and appeared more pronounced in children than adults.

SUBMITTER: Vesper HW

PROVIDER: S-EPMC5698798 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature

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Serum Total Testosterone Concentrations in the US Household Population from the NHANES 2011-2012 Study Population.

Vesper Hubert W HW Wang Yuesong Y Vidal Meghan M Botelho Julianne Cook JC Caudill Samuel P SP

Clinical chemistry 20151028 12

<h4>Background</h4>Limited information is available about testosterone concentrations representative of the general US population, especially children, women, and non-Hispanic Asians.<h4>Methods</h4>We obtained nationally representative data for total testosterone (totalT), measured with standardized LC-MS/MS, for the US population age 6 years and older from the 2011-2012 National Health and Nutrition Examination Survey (NHANES). We analyzed 6746 serum samples and calculated the geometric means, ...[more]

PMID: 26510959

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Dataset Information

Serum Total Testosterone Concentrations in the US Household Population from the NHANES 2011-2012 Study Population.

Publications

Serum Total Testosterone Concentrations in the US Household Population from the NHANES 2011-2012 Study Population.

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