Ontology highlight
ABSTRACT:
SUBMITTER: Manojlovic Z
PROVIDER: S-EPMC5699827 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Manojlovic Zarko Z Christofferson Austin A Liang Winnie S WS Aldrich Jessica J Washington Megan M Wong Shukmei S Rohrer Daniel D Jewell Scott S Kittles Rick A RA Derome Mary M Auclair Daniel D Craig David Wesley DW Keats Jonathan J Carpten John D JD
PLoS genetics 20171122 11
Multiple Myeloma (MM) is a plasma cell malignancy with significantly greater incidence and mortality rates among African Americans (AA) compared to Caucasians (CA). The overall goal of this study is to elucidate differences in molecular alterations in MM as a function of self-reported race and genetic ancestry. Our study utilized somatic whole exome, RNA-sequencing, and correlated clinical data from 718 MM patients from the Multiple Myeloma Research Foundation CoMMpass study Interim Analysis 9. ...[more]