Ontology highlight
ABSTRACT:
SUBMITTER: Barnoud J
PROVIDER: S-EPMC5700758 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
PeerJ 20171120
This paper describes the development and application of a suite of tools, called PBxplore, to analyze the dynamics and deformability of protein structures using Protein Blocks (PBs). Proteins are highly dynamic macromolecules, and a classical way to analyze their inherent flexibility is to perform molecular dynamics simulations. The advantage of using small structural prototypes such as PBs is to give a good approximation of the local structure of the protein backbone. More importantly, by reduc ...[more]