Rapid resetting of human peripheral clocks by phototherapy during simulated night shift work.
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ABSTRACT:
SUBMITTER: Cuesta M
PROVIDER: S-EPMC5701225 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Publications
Rapid resetting of human peripheral clocks by phototherapy during simulated night shift work.
Cuesta Marc M Boudreau Philippe P Cermakian Nicolas N Boivin Diane B DB
Scientific reports 20171124 1
A majority of night shift workers have their circadian rhythms misaligned to their atypical schedule. While bright light exposure at night is known to reset the human central circadian clock, the behavior of peripheral clocks under conditions of shift work is more elusive. The aim of the present study was to quantify the resetting effects of bright light exposure on both central (plasma cortisol and melatonin) and peripheral clocks markers (clock gene expression in peripheral blood mononuclear c ...[more]
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