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ABSTRACT: Objective
The objective of this study was to investigate both the effects of low gestational age and infant's neurodevelopmental outcome at 2 years of age on the risk of parental separation within 7 years of giving birth.Design
Prospective.Setting
24 maternity clinics in the Pays-de-la-Loire region.Participants
This study included 5732 infants delivered at <35 weeks of gestation born between 2005 and 2013 who were enrolled in the population-based Loire Infant Follow-up Team cohort and who had a neurodevelopmental evaluation at 2 years. This neurodevelopmental evaluation was based on a physical examination, a psychomotor evaluation and a parent-completed questionnaire.Outcome measure
Risk of parental separation (parents living together or parents living separately).Results
Ten percent (572/5732) of the parents reported having undergone separation during the follow-up period. A mediation analysis showed that low gestational age had no direct effect on the risk of parental separation. Moreover, a non-optimal neurodevelopment at 2 years was associated with an increased risk of parental separation corresponding to a HR=1.49(1.23 to 1.80). Finally, the increased risk of parental separation was aggravated by low socioeconomic conditions.Conclusions
The effect of low gestational age on the risk of parental separation was mediated by the infant's neurodevelopment.
SUBMITTER: Nusinovici S
PROVIDER: S-EPMC5701975 | biostudies-literature |
REPOSITORIES: biostudies-literature