Ontology highlight
ABSTRACT:
SUBMITTER: Brea RJ
PROVIDER: S-EPMC5702554 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Brea Roberto J RJ Cole Christian M CM Lyda Brent R BR Ye Libin L Prosser R Scott RS Sunahara Roger K RK Devaraj Neal K NK
Journal of the American Chemical Society 20170306 10
Cell transmembrane receptors play a key role in the detection of environmental stimuli and control of intracellular communication. G protein-coupled receptors constitute the largest transmembrane protein family involved in cell signaling. However, current methods for their functional reconstitution in biomimetic membranes remain both challenging and limited in scope. Herein, we describe the spontaneous reconstitution of adenosine A<sub>2A</sub> receptor (A<sub>2A</sub>R) during the de novo forma ...[more]