Ontology highlight
ABSTRACT:
SUBMITTER: Kaplan AP
PROVIDER: S-EPMC5702621 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Frontiers in medicine 20171122
The unpredictable nature of attacks of tissue swelling in hereditary angioedema requires the identification of reliable biomarkers to monitor disease activity as well as response to therapy. At present, one can assess a C4 level (by ELISA) to assist in diagnosis but neither C4 nor C1 inhibitor levels reflect clinical course or prognosis. We will here review a collection of plasma proteins involved in blood coagulation, fibrinolysis, and innate immunity (Figure 1). A main focus is those proteins ...[more]