Ictal source imaging and electroclinical correlation in self-limited epilepsy with centrotemporal spikes.

ABSTRACT:

Purpose

To elucidate the localization of ictal EEG activity, and correlate it to semiological features in self-limited epilepsy with centrotemporal spikes (formerly called "benign epilepsy with centrotemporal spikes").

Methods

We have performed ictal electric source imaging, and we analysed electroclinical correlations in three patients with self-limited epilepsy with centrotemporal spikes.

Results

The source of the evolving rhythmic ictal activity (9.7-13.5Hz) localized to the operculo-insular area. The rhythmic EEG activity was time-locked to the contralateral focal motor seizure manifestation: facial rhythmic myoclonic jerks, with the same frequency as the analysed ictal rhythm. In all three patients, the seizures had fluctuating course with pauses of clinical and

SUBMITTER: Alving J 

PROVIDER: S-EPMC5703029 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature