Ontology highlight
ABSTRACT:
SUBMITTER: Jaigirdar SA
PROVIDER: S-EPMC5705559 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Jaigirdar Shafqat Ahrar SA Benson Robert A RA Elmesmari Aziza A Kurowska-Stolarska Mariola Stefania MS McInnes Iain B IB Garside Paul P MacLeod Megan K L MKL
Frontiers in immunology 20171124
Inflammation can be protective or pathogenic depending on context and timeframe. Acute inflammation, including the accumulation of CD4 T cells, accompanies protective immune responses to pathogens, but the presence of activated CD4 T cells at sites of inflammation is associated with chronic inflammatory disease. While significant progress has been made in understanding the migration of CD4 T cells into inflamed sites, the signals that lead to their persistence are poorly characterized. Using a m ...[more]