Ontology highlight
ABSTRACT:
SUBMITTER: Dou H
PROVIDER: S-EPMC5705620 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Dou Huiqiang H Shen Renhui R Tao Jianxin J Huang Longchang L Shi Haoze H Chen Hang H Wang Yixin Y Wang Tong T
Frontiers in pharmacology 20171124
Curcumin exhibits anti-tumor effects in several cancers, including colorectal carcinoma (CRC), but the detailed mechanisms are still unclear. Here we studied the mechanisms underlying the anti-tumor effect of curcumin in colon cancer cells. SW480 cells were injected into mice to establish the xenograft tumor model, followed by evaluation of survival rate with the treatment of curcumin. The expression levels of β-catenin, Axin and TCF4 were measured in the SW480 cells in the absence or presence o ...[more]