Ontology highlight
ABSTRACT:
SUBMITTER: Kwon J
PROVIDER: S-EPMC5705720 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Nature communications 20171128 1
In the mammalian nervous system, myelin provides electrical insulation for the neural circuit by forming a highly organized, multilayered thin film around the axon fibers. Here, we investigate the spectral reflectance from this subcellular nanostructure and devise a new label-free technique based on a spectroscopic analysis of reflected light, enabling nanoscale imaging of myelinated axons in their natural living state. Using this technique, we demonstrate three-dimensional mapping of the axon d ...[more]