Exolysin Shapes the Virulence of Pseudomonas aeruginosa Clonal Outliers.
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ABSTRACT:
SUBMITTER: Reboud E
PROVIDER: S-EPMC5705979 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Publications
Exolysin Shapes the Virulence of Pseudomonas aeruginosa Clonal Outliers.
Reboud Emeline E Basso Pauline P Maillard Antoine P AP Huber Philippe P Attrée Ina I
Toxins 20171109 11
Bacterial toxins are important weapons of toxicogenic pathogens. Depending on their origin, structure and targets, they show diverse mechanisms of action and effects on eukaryotic cells. Exolysin is a secreted 170 kDa pore-forming toxin employed by clonal outliers of <i>Pseudomonas aeruginosa</i> providing to some strains a hyper-virulent behaviour. This group of strains lacks the major virulence factor used by classical strains, the Type III secretion system. Here, we review the structural feat ...[more]
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