Ontology highlight
ABSTRACT:
SUBMITTER: Chretien AS
PROVIDER: S-EPMC5706596 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Chretien Anne-Sophie AS Devillier Raynier R Fauriat Cyril C Orlanducci Florence F Harbi Samia S Le Roy Aude A Rey Jérôme J Bouvier Borg Gaelle G Gautherot Emmanuel E Hamel Jean-François JF Ifrah Norbert N Lacombe Catherine C Cornillet-Lefebvre Pascale P Delaunay Jacques J Toubert Antoine A Arnoulet Christine C Vey Norbert N Blaise Didier D Olive Daniel D
Oncoimmunology 20170324 12
NKp46 is a major determinant of natural killer (NK) cell function and it is implicated in tumor immune surveillance in acute myeloid leukemia (AML). The purpose of this study was to investigate the prognostic significance of NKp46 expression in an independent cohort of patients with AML, and to investigate the impact of NKp46 on clinical outcome after allogeneic stem cell transplantation (allo-SCT). NKp46 expression was assessed at diagnosis on NK cells by flow cytometry (N = 180 patients). Clin ...[more]