Development of diagnostic model of lung cancer based on multiple tumor markers and data mining.
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ABSTRACT:
SUBMITTER: Wang Z
PROVIDER: S-EPMC5706913 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Publications
Development of diagnostic model of lung cancer based on multiple tumor markers and data mining.
Wang Zhaoxian Z Feng Feifei F Zhou Xiaoshan X Duan Liju L Wang Jing J Wu Yongjun Y Wang Na N
Oncotarget 20171019 55
<h4>Objective</h4>To develop early intelligent discriminative model of lung cancer and evaluate the efficiency of diagnosis value.<h4>Methods</h4>Based on the genetic polymorphism profile of CYP1A1-rs1048943, GSTM1, mEH-rs1051740, XRCC1-rs1799782 and XRCC1-rs25489 and the methylations of p16 and RASSF1A gene, and the length of telomere in the peripheral blood from 200 lung cancer patients and 200 health persons, the discriminative model was established through decision tree and ANN technique.<h4 ...[more]
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