Ontology highlight
ABSTRACT:
SUBMITTER: Ng DYW
PROVIDER: S-EPMC5707410 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Ng David Y W DYW Vill Roman R Wu Yuzhou Y Koynov Kaloian K Tokura Yu Y Liu Weina W Sihler Susanne S Kreyes Andreas A Ritz Sandra S Barth Holger H Ziener Ulrich U Weil Tanja T
Nature communications 20171129 1
Self-assembly in situ, where synthetic molecules are programmed to organize in a specific and complex environment i.e., within living cells, can be a unique strategy to influence cellular functions. Here we present a small series of rationally designed oligothiophene analogues that specifically target, locate and dynamically self-report their supramolecular behavior within the confinement of a cell. Through the recognition of the terminal alkyl substituent and the amphiphilic pyridine motif, we ...[more]