Ontology highlight
ABSTRACT:
SUBMITTER: Raza AL
PROVIDER: S-EPMC5707480 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Chemical science 20150526 7
C-F activation of 2,3,5,6-tetrafluoropyridine at [Rh{Si(OEt)<sub>3</sub>}(PEt<sub>3</sub>)<sub>3</sub>] (<b>1</b>) yields [Rh{2-(3,5,6-C<sub>5</sub>F<sub>3</sub>HN)}(PEt<sub>3</sub>)<sub>3</sub>] (<b>2</b>) and FSi(OEt)<sub>3</sub>, but in an unprecedented consecutive reaction FSi(OEt)<sub>3</sub> acts as a fluoride source to give [Rh(4-C<sub>5</sub>F<sub>4</sub>N)(PEt<sub>3</sub>)<sub>3</sub>] (<b>4</b>) by regeneration of the C-F bond and C-H activation. Analogous refluorination steps were obs ...[more]