The Association between Serum 25(OH)D Status and Blood Pressure in Participants of a Community-Based Program Taking Vitamin D Supplements.

ABSTRACT:

Background

Vitamin D deficiency is a risk factor for hypertension.

Methods

We assessed 8155 participants in a community-based program to investigate the association between serum 25-hydroxyvitamin D (25(OH)D) status and blood pressure (BP) and the influence of vitamin D supplementation on hypertension. Participants were provided vitamin D supplements to reach a target serum 25(OH)D > 100 nmol/L. A nested case-control study was conducted to examine the effect of achieving physiological vitamin D status in those who were hypertensive and not taking BP-lowering medication, and hypertensive participants that initiated BP-lowering medication after program entry.

Results

At baseline, 592 participants (7.3%) were hypertensive; of those, 71% were no longer hypertensive at fol

SUBMITTER: Mirhosseini N 

PROVIDER: S-EPMC5707716 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature